Please use one of the following formats to cite this article in your essay, paper or report university of illinois-chicago, drug information g. No direct etiologic relationship to concurrent clindamycin therapy could be made in any of the foregoing. The extent of absorption, however, is not different between age groups and no dosage alteration is necessary for the elderly with normal hepatic function and normal (age-adjusted) renal function clindamycin inhibits bacterial protein synthesis by binding to the 23s rna of the 50s subunit of the resistance to clindamycin is most often caused by modification of specific bases of the 23s.
However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. Talk to your doctor about other drug options that may work for you. Cleocin hcl is contraindicated in individuals with a history of hypersensitivity to preparations containing clindamycin or lincomycin.
Skipping doses or not completing the full course of therapy may (1) decrease the effectiveness of the immediate treatment and (2) increase the likelihood that bacteria will develop resistance and will not be treatable by cleocin hcl or other antibacterial drugs in the future. It comes as the brand-name drugs prozac and prozac weekly, and as a generic drug. You may need to show airport staff the pharmacy label for your medication.
Because of the risk of , as described in the boxed warning, before selecting clindamycin, the physician should consider the nature of the infection and the suitability of less toxic alternatives (e. A black box warning alerts doctors and patients about drug effects that may be dangerous. However, animal studies dont always predict the way humans would respond.
Absorption of an oral dose is virtually complete (90), and the concomitant administration of food does not appreciably modify the serum concentrations serum levels have been uniform and predictable from person to person and dose to dose. If your symptoms are severe, call 911 or go to the nearest emergency room right away. Levels of ddt, a once-common pesticide, in maternal blood have been linked with an increased risk of autism in the offspring in a new study.
Because of possible clinical significance, these two drugs should not be administered concurrently. This category also provides a buffer zone that prevents small, uncontrolled technical factors from causing major discrepancies in interpretation. Its available as a generic drug and as the brand-name drugs dexpak and decadron. Hcl and may range in severity from mild diarrhea to fatal because cleocin hcl therapy has been associated with severe colitis which may end fatally, it should be reserved for serious infections where less toxic section. The use of cleocin hcl occasionally results in overgrowth of nonsusceptible organismsparticularly yeasts.
Because of possible clinical significance, these two drugs should not be administered concurrently. This procedure uses paper disks impregnated with 2 mcg of clindamycin to test the susceptibility of bacteria to clindamycin. A black box warning alerts doctors and patients about drug effects that may be dangerous. In some cases, they may not be available in all strengths or forms as the brand-name drug. Because animal reproduction studies are not always predictive of the human response, this drug should be used during pregnancy only if clearly needed.
Serum level studies following multiple doses of cleocin hcl for up to 14 days show no evidence of accumulation or altered of drug. Severe skin reactions such as toxic and abnormalities in liver function tests have been observed during clindamycin therapy. When available, the clinical microbiology laboratory should provide cumulative drugs used in local hospitals and practice areas to the physician as periodic reports that describe the susceptibility profile of pathogens. It should not be used in patients with nonbacterial infections such as most upper respiratory tract infections. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.
These reports should aid the physician in selecting an antibacterial drug for treatment. To reduce the development of drug-resistant bacteria and maintain the effectiveness of cleocin hcl and other drugs, cleocin hcl should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. However, other reported clinical experience indicates that antibiotic-associated colitis and diarrhea (due to ) seen in association with most antibiotics occur more frequently in the elderly ( 60 years) and may be more severe. You should always consult your doctor or other healthcare professional before taking any medication. There havent been enough studies done in pregnant women during the first trimester to show if the drug poses a risk to a human pregnancy during that time. Your medication may not work as well or may stop working completely. Smith rb, phillips jp evaluation of cleocin hcl and cleocin phosphate in an aged population. Review of experience to date suggests that a subgroup of older patients with associated severe illness may tolerate diarrhea less well. Clindamycin dosage modification may not be necessary in patients with renal disease. If you dont take this drug, your infection wont get better.May 15, 2018 ... Clindamycin: learn about side effects, dosage, special precautions, and more on MedlinePlus. ... Take the capsules with a full glass of water so that the medication will not irritate your throat. ... If your symptoms do not improve or if they get worse, call your doctor. .... Page last updated: 30 July 2018. Return to ...